Review of 16 published scientific articles on the efficacy of naproxen sodium as a treatment of acute migraine indicates that it is effective in the treatment of moderate to severe migraines. Naproxen sodium, 500 mg (2 tablets of Aleve) provided some relief after 2 hours to 45% of patients, complete pain relief to 17% and complete relief after 24 hours to 11%. Aspirin, 1,000 mg (2 extra-strength tablets) has been shown to do better, providing 52%, 27% and 24% of relief, respectively. Both naproxen sodium and aspirin relieve all of the migraine symptoms, including pain, nausea, sensitivity to light and noise.
