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by Dr. Alexander Mauskop
October 2, 2021
FDA approves Qulipta (atogepant), a new preventive migraine drug
October 2, 2021
Atogepant (Qulipta) is a new migraine drug that was just approved by the FDA for the preventive treatment of migraines. It is the third drug in the family of gepants. Gepants block the CGRP receptor. CGRP is a chemical...
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September 27, 2021
A large study shows that the weather affects pain
September 27, 2021
Many migraine sufferers report that their migraines are brought on by the weather. High humidity, high temperatures, and changes in barometric pressure are the most commonly reported triggers. I’ve seen some patients for whom...
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September 18, 2021
Migraines are less common in people with diabetes
September 18, 2021
Two large studies have established that if you have diabetes you are less likely to suffer from migraines. The first study was done on the entire population of Norway. The authors concluded that both type 1 and type 2 diabetes...
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September 11, 2021
Julie Mauskop on David Zwirner’s Platform
September 11, 2021
Patients coming to the New York Headache Center have enjoyed seeing my daughter Julie’s artwork since she was 11. This was not just a childhood interest – Julie graduated from the Rhode Island School of Design with a degree...
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September 6, 2021
A new, better DHE nasal spray is approved for acute migraines
September 6, 2021
Trudhesa is a new formulation of dihydroergotamine (DHE) nasal spray just approved by the FDA. It appears to be more effective than the original DHE nasal spray (Migranal) that was introduced in 1997. Ergotamine, the first migraine...
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August 30, 2021
Placebo really works, even if you know it’s placebo
August 30, 2021
The placebo effect is a bane of clinical trials. A drug is considered ineffective if it is only as good as a placebo. And placebo can be quite good. Intriguingly, the placebo effect in clinical trials has been getting stronger over the past...
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August 22, 2021
Another review of The End of Migraines: 150 Ways to Stop Your Pain
August 22, 2021
It is gratifying to know that my colleagues consider my new book, The End of Migraines: 150 Ways to Stop Your Pain, to be useful for patients with migraines as well as doctors who treat them. Dr. Uwe Reuter of Charité Universitätsmedizin...
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August 8, 2021
More of the omega-3 and less of omega-6 fatty acids helps migraines
August 8, 2021
Migraine can be triggered by many foods, including sugar, chocolate, smoked, pickled, cured, dried, and fermented foods. There are also foods that can help with migraines. These are magnesium-rich dark leafy vegetables...
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August 2, 2021
Magnesium can reduce the risk of aneurysm formation and rupture
August 2, 2021
Many patients with headaches are concerned about having a brain aneurysm. It is rare for an aneurysm to cause ongoing headaches. An aneurysm usually causes one very severe headache when it ruptures and causes...
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July 26, 2021
Naratriptan is the most effective triptan?
July 26, 2021
In the US, we are lucky to have seven different triptans available in the pharmacies. Five of them – sumatriptan, rizatriptan, zolmitriptan, eletriptan, and almotriptan are considered to be more effective than the other two – naratriptan...
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July 17, 2021
Chronic pain causes cognitive decline
July 17, 2021
Many patients with chronic migraines complain of memory, word-finding, and other cognitive difficulties. I tell them that once we find an effective treatment for their migraines, their cognitive abilities should improve...
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July 10, 2021
Occipital nerve stimulation relieves chronic cluster headaches
July 10, 2021
The pain of cluster headaches is considered to be the worst of all headaches. Hence the moniker, suicide headaches. Thankfully, it is a rare condition. Episodic cluster headaches affect a little over 0.1% of the population or approximately...
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June 28, 2021
Mindfulness-based stress reduction helps migraines
June 28, 2021
It’s been a few years since I wrote about meditation. There is little doubt that it helps migraine sufferers. Unlike drugs, meditation is harder to test in clinical trials. However, we do have many imaging studies showing the effect...
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June 17, 2021
Dividing migraines into chronic and episodic was a costly mistake
June 17, 2021
The international classification of headache disorders lists many different types of migraines – migraine with aura, hemiplegic, retinal, chronic, and others. Chronic migraine is present if a person has a headache on 15 or more...
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June 7, 2021
Erenumab relieves trigeminal neuralgia – another case series
June 7, 2021
Trigeminal neuralgia (TN) is an extremely painful and often debilitating condition. Many people respond to the standard therapy with epilepsy drugs such as carbamazepine (Tegretol) or oxcarbazepine (Trileptal). Botox injections...
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June 2, 2021
Dr. Allan Purdy’s review of my new book
June 2, 2021
A publication of the American Headache Society, Headache, The Journal of Head and Face Pain, has just published Dr. Allan Purdy’s most generous review of my new book, The End of Migraines: 150 Ways to Stop Your Pain...
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May 27, 2021
Nurtec is the first drug approved for acute and preventive treatment of migraines
May 27, 2021
Biohaven, the manufacturer of rimegepant (Nurtec ODT) just received FDA approval to market this drug for the prevention of migraines. Rimegepant was approved in January of 2020 for the acute treatment of migraine headaches...
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May 23, 2021
Predicting success of surgery for trigeminal neuralgia
May 23, 2021
Trigeminal neuralgia (TN) is an extremely painful condition. Patients describe the pain as electric shocks going through the face. The most common or classic form of TN is caused by the compression of the trigeminal nerve as...
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May 17, 2021
The pendulum swings and hits hard patients on opioid drugs
May 17, 2021
The opioid epidemic has claimed many lives. Overprescribing by doctors has certainly played a role. The push to use opioids more liberally started in the late 1980s. This promotion by many pain experts even led to pain...
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May 9, 2021
ER treatment of posttraumatic headaches
May 9, 2021
Almost 1.5 million Americans visit emergency rooms every year for the treatment of head trauma. Headache, not surprisingly, is one of the most common symptoms of head trauma. What is very surprising is that until now, there...
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May 2, 2021
Skipping breakfast, lack of greenery, and other factors that may predispose kids to headaches.
May 2, 2021
We know that physical emotional, and sexual abuse in childhood increases the risk of developing chronic pain and migraines later in life. Dutch researchers looked at several other potential predisposing factors. The results of their...
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April 24, 2021
Post-traumatic headaches are mostly migraines
April 24, 2021
Post-traumatic headaches (PTH) are classified as a distinct category of headaches. There is growing evidence, however, that headaches that develop after a head injury are migraines. A study just published in Cephalalgia by Dr...
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April 18, 2021
The description of neuropathic pain predicts response to Botox
April 18, 2021
The goal of personalized medicine will be achieved through the exponential growth of computing power. Epigenetics, pharmacogenomics, and machine learning are some of the approaches that are being driven by our ability...
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April 10, 2021
Magnesium enhances the migraine prevention effect of valproate
April 10, 2021
This blog has many posts about the role of magnesium in the prevention of migraines and clinical trials of magnesium. Another study was just published by Iranian doctors in The Journal of Headache and Pain. Unfortunately, like other studies...
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April 1, 2021
Dramatic weight loss with a diabetes drug; may help migraines and other neurological problems
April 1, 2021
Weight loss in overweight migraine sufferers – including that produced by bariatric surgery – leads to a reduction in the frequency of migraine attacks. In a previous post and in my new book I mentioned the use of metformin...
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March 21, 2021
Bidirectional association between loneliness and pain
March 21, 2021
COVID-related lockdowns have saved many lives. We don’t yet fully appreciate, however, the other side of the ledger – the harms the lockdowns have caused. These include delays in diagnosing cancers, alcohol and drug abuse...
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March 13, 2021
Low cerebrospinal fluid pressure headache
March 13, 2021
The headache of low cerebrospinal fluid (CSF) pressure can be very severe. Its main feature is that it gets worse on sitting or standing and improves upon lying down. Sometimes, this change is quick but occasionally the...
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March 6, 2021
Postural orthostatic tachycardia syndrome (POTS) and migraine
March 6, 2021
The term postural orthostatic tachycardia means that the heart rate becomes very fast upon standing up. POTS is a disorder of the autonomic nervous system that is associated with abnormal blood flow regulation. Almost all patients...
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February 25, 2021
Cyclic vomiting, a migraine variant
February 25, 2021
Cyclic vomiting is considered to be a form of migraine. It is most common in children. Surveys indicate that 2% to 3% of children may be suffering from this condition. These children often develop typical migraines as they get...
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February 18, 2021
Low dietary intake of magnesium increases the risk of migraines
February 18, 2021
Magnesium supplementation for the prevention of migraine headaches has been gaining wider acceptance. Dozens of studies, including several of our own, have shown that migraine sufferers often have a magnesium deficiency...
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Insights from Dr. Alexander Mauskop on headaches and migraines
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