New drug for migraine prevention

February 13, 2008

A new drug may be better for the prevention of migraines than the old ones in the same category.  A study just published in Headache suggests that nebivolol, a beta-blocker just approved in the US for the treatment of high blood pressure may be as effective as old beta-blockers, but with significantly fewer side effects. Beta-blockers, such as propranolol (Inderal), timolol (Blocadren) metoprolol (Toprol), atenolol (Tenormin) and nadolol (Corgard) have been used for the prevention of migraines for many years. However, many patients could not tolerate them because of side effects, mostly fatigue, slow heart beat and low blood pressure. Nebivolol appears to cause these side effects 50% less often, while preventing migraine attacks with equal efficacy.

Written by
Alexander Mauskop, MD
Continue reading
December 15, 2025
Alternative Therapies
Could drugs like Ozempic, Saxenda, and Zepbound help migraines?
Could drugs like Ozempic, Saxenda, and Zepbound help migraines? Extra weight often increases migraine headache frequency and makes standard treatments less effective. But a study just published in the journal Headache shows that a medication commonly used for weight loss and diabetes, liraglutide (Saxenda), might offer relief for tough-to-treat migraines in people with obesity.
Read article
November 15, 2025
Cluster headaches
Cluster headaches and solar activity
It was an unusual week at the New York Headache Center. After months of relative calm, my schedule suddenly filled with cluster headache patients—one even consulting me virtually from Saudi Arabia. The influx came right after a G5-level geomagnetic storm, one of the strongest solar events in recent memory.
Read article
November 10, 2025
Alternative Therapies
A Week of Meditation Changes Brains and Bodies
A week-long meditation retreat produces dramatic changes in brain and metabolic functions
Read article