Research

A New Study of Meat Intake, Genetics, and Brain Health

June 4, 2026

A recent study from Sweden found that older adults who atemore meat had slower cognitive decline and a lower risk of dementia, but onlyif they carried a specific genetic risk factor for Alzheimer’s disease (APOEE3/E4 or E4/E4).

The study included 2,157 adults aged 60 or older withoutdementia who were followed for up to 15 years.

This was an observational study, so it does not show thatmeat prevents dementia. It does suggest that diet and brain health may interactwith genetics.

One important finding from this study is that all participantshad a higher risk of dementia if they had a higher intake of processed meat,such as bacon and deli meats.

Another interesting detail is what the meat replaced in thediet. The association was strongest when meat replaced foods like cereals anddairy, not when it replaced fish or eggs.

From a headache and migraine perspective, there may beanother explanation worth considering. Diets higher in meat are often lower incarbohydrates, which can shift metabolism toward using ketones for energy.Ketogenic strategies are helpful for some patients with migraine and supportbrain energy metabolism. A rare form of childhood epilepsy respondsdramatically to a ketogenic diet.

It is possible that some of the observed benefits relate tothis metabolic effect rather than meat itself. This is especially relevant inAPOE4 carriers, in whom differences in brain energy use have been reported.

The study also noted that some of the benefits could be dueto higher levels of vitamin B12 in meat, but these findings remain preliminary.

For now, this research does not change standardrecommendations. The most consistent evidence still supports diets built aroundwhole, minimally processed foods, with limited processed meat.

This study adds support for a more individualized view ofnutrition, in which genetics and metabolism may influence how the brainresponds to diet.

Written by
Alexander Mauskop, MD
Continue reading
June 3, 2026
News
Keynote address at the 22nd Annual Neuroscience Zappulla Research Day
I was honored to be delivering the keynote address at the 22nd Annual Neuroscience Zappulla Research Day on Wednesday, June 3, at the Hackensack Meridian Neuroscience Institute, JFK University Medical Center in Edison, NJ.
Read article
May 26, 2026
News
Why I Rarely Prescribe Topiramate, and What the New Data Shows
A new real-world study of 661 patients found that 67% stopped taking topiramate within six months, compared to 30% on candesartan. Candesartan also had a higher responder rate. Topiramate is FDA-approved; candesartan is not. The data makes the case for rethinking that priority.
Read article
May 21, 2026
Research
Your Brain Has Many Pathways, And TMS Can Now Use Them
A groundbreaking University of Iowa study shows that personalized fMRI-guided TMS can now reach and modulate the deep hippocampus — the brain’s command center for memory, emotion, and migraine — without surgery or heavy medications. By mapping each patient’s unique neural pathways, TMS delivers precise stimulation to surface “control points” that influence deep brain structures. Generic approaches barely work, but individualized targeting produces clear, measurable changes. At our headache clinic, we combine TMS and fMRI to offer this advanced, personalized treatment for migraines, depression, PTSD, anxiety, and more.
Read article
Insights from Dr. Alexander Mauskop on headaches and migraines
Subscribe to the Blog.
Subscribe
Subscribe