Transcranial Magnetic Stimulation for Pain

May 21, 2025

We have been using repetitive transcranial magnetic stimulation (rTMS) to treat chronic migraine headaches and other types of pain and neurological disorders. An article published in Pain Medicine News provides a brief review of the use of rTMS in treating painful conditions. rTMS has been reported to relieve neuropathic pain, orofacial pain, phantom pain, low back pain, myofascial pain syndrome, pelvic pain, and complex regional pain syndrome.

A recent study published in the journal Pain suggests that chronic low back pain may be related to the dysfunction in the periaqueductal gray (PAG), a brain region involved in pain regulation. This finding highlights the potential for brain-targeted therapies such as TMS.

rTMS is a non-invasive treatment, and it might help reduce pain by modulating brain regions involved in pain processing. Although more studies are needed, rTMS could offer a drug-free option for those with persistent low back pain.

rTMS of the brain is approved by the FDA to treat anxiety, depression, OCD, and nicotine addiction. rTMS is also approved to treat peripheral pain by applying rTMS to the area of pain. This involves using a magnetic coil on an arthritic joint, an area of back pain, or any other body part.

Getting an FDA approval for chronic migraines or other painful conditions is a lengthy and expensive process. For-profit companies will not invest millions of dollars in this project since rTMS treatment is difficult to patent. The funding will need to come from the NIH or non-profit foundations. We do need FDA approval in order to have insurance companies to pay for this treatment.

Written by
Alexander Mauskop, MD
Continue reading
June 7, 2026
News
A new edition of my migraine book and an upcoming conversation with Dr. Sanjay Gupta
An overview of why I updated The End of Migraines: 150 Ways to Stop Your Pain for a 3rd edition, what has changed in migraine treatment, and how a more structured, realistic approach can help people who feel they’ve “tried everything.”
Read article
June 4, 2026
Research
A New Study of Meat Intake, Genetics, and Brain Health
A newly published Swedish study suggests that the relationship between diet and brain aging may be more genetically specific than previously understood. Researchers followed over 2,000 older adults for up to 15 years and found that higher meat consumption was associated with slower cognitive decline and lower dementia risk, but only in those carrying the APOE E4 genetic variant, the most common hereditary risk factor for Alzheimer's disease. This may be relevant for people with headaches.
Read article
June 3, 2026
News
Keynote address at the 22nd Annual Neuroscience Zappulla Research Day
I was honored to be delivering the keynote address at the 22nd Annual Neuroscience Zappulla Research Day on Wednesday, June 3, at the Hackensack Meridian Neuroscience Institute, JFK University Medical Center in Edison, NJ.
Read article
Insights from Dr. Alexander Mauskop on headaches and migraines
Subscribe to the Blog.
Subscribe
Subscribe