Prodrome to migraine headaches

October 4, 2012

Prodrome refers to symptoms that precede an actual attack of migraine. Migraine aura also precedes an attack, but it occurs 20 to 60 minutes before the headache and typically consists of visual disturbances or partial visual loss. Prodrome typically is a period of 24 to 48 hours before a migraine attack and it can consist of a wide variety of symptoms. Many people are aware that these symptoms indicate an impending migraine attack, but some are not. Some people tell me that when they feel unusually full of energy, very happy, and creative they realize that they will get a headache the next day. And some realize that what was happening to them was a prodrome only in retrospect, even after having all of the same symptoms repeat themselves many times. Not many people experience prodrome and its features are varied. Here are some of the symptoms reported in the prodrome period:

Depression
Euphoria
Irritability
Restlessness
Hyperactivity
Fatigue
Drowsiness
Difficulty concentrating
Neck or other muscle stiffness
Feeling hot or coldIncreased thirst
Increased urination
Food cravings
Loss of appetite
Yawning
Tearing
Constipation
Diarrhea
Fluid retention
Sensitivity to light and/or sound

If you do experience a prodrome and are aware of it while it is happening, taking an anti-inflammatory medication (Advil, Aleve, Migralex) or, if that does not work, a triptan may prevent an attack or at least make it milder.

Written by
Alexander Mauskop, MD
Continue reading
September 17, 2026
Music and Pain
Music can relieve pain, but what kind of music? A new study from McGill University, published in Pain, found that music with greater emotional depth reduced pain, while intense, forceful music increased it. The effect seemed to depend on how much listeners enjoyed the music. The practical advice: choose music you love, rather than music labeled relaxing or therapeutic.
Read article
September 10, 2026
Brain disorders
Genetic connection of fibromyalgia with low back pain, PTSD, IBS, and other disorders.
A genome-wide study published in Nature Medicine found that fibromyalgia shares genetic risk factors with chronic pain conditions, IBS, PTSD, and sleep disturbances. This supports treating these overlapping conditions as one problem of a hyperexcitable nervous system rather than as separate diseases, using a multidisciplinary approach that combines psychological therapies with medications, injections, and neurostimulation.
Read article
Insights from Dr. Alexander Mauskop on headaches and migraines
Subscribe to the Blog.
Subscribe
Subscribe