Occipital microstimulator

May 26, 2009

Occipital nerve stimulation appears to be a promising new treatment for migraine and cluster headaches. Phase II trials performed by Medtronics, the manufacturer of one type of  stimulator, have been positive. This stimulator requires implantation of a stimulator wire next to the occipital nerves and a separate incision to implant a stimulator device with a battery in the upper chest. A recent report suggests that the same effect can be achieved by implanting a small self-contained device without the need for wires, large battery, or a separate incision. This “Bion Microstimulator” has not been subjected to any extensive studies similar to ones  performed by Medtronics, but the preliminary data looks promising.

Written by
Alexander Mauskop, MD
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Research
An Old Medicine that Could Make Brain Stimulation Work Better for Depression and Other Neurological Conditions
A 2022 clinical trial from the University of Calgary found that adding low‑dose D‑cycloserine (DCS), a partial NMDA‑receptor agonist, to intermittent theta‑burst stimulation (iTBS) significantly increased response and remission rates in depression without serious side effects. Early follow‑up data suggest that timing, dose, and drug levels matter, and raise the possibility that this DCS‑TMS approach could eventually be applied to other neurological conditions—such as migraine, postconcussion syndrome, brain fog, and long COVID
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Insights from Dr. Alexander Mauskop on headaches and migraines
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