Light and headaches

January 11, 2010

Migraines in blind people are made worse by light, according to Dr. Burstein and his associates at Harvard. Rami Burstein is one of the leading headache researchers who often asks questions no one else thought to ask. More importantly, he often finds the answers. When he mentioned to me that he wants to find out why bright light makes headaches worse (so called photophobia), I immediately thought of a blind patient I was treating. She was very interested in helping Rami discover the answer and helped him recruit many other blind migraine sufferers. After several years of work, his finding were published today in Nature Neuroscience. A recent discovery showed that in addition to rods and cones in the retina (cells that allow us to see), there are cells which react to light, but their input goes to non-visual parts of the brain. These cells regulate sleep-wake cycle and, according to Rami Burstein’s research, also magnify pain perception in headache patients.

Written by
Alexander Mauskop, MD
Continue reading
September 7, 2025
How Artificial Sweeteners May Be Affecting Your Brain
A large Brazilian study published in Neurology followed nearly 13,000 adults for eight years and found something troubling: people who consumed the most artificial sweeteners showed faster cognitive...
Read article
August 30, 2025
Lithium Levels are low in Alzheimer’s. Is there a role in Migraine and Chronic Pain?
Recently published research on lithium deficiency in Alzheimer’s disease has caught the attention of the media. As a neurologist specializing in pain and headache medicine with an interest in no...
Read article
August 16, 2025
The Healing Power of Holding Hands: Insights from Neuroscience on Pain Relief
There’s something powerful about human touch when you’re hurting. As a neurologist, I see every day how a gentle hand squeeze from someone you trust can shift your pain—not just emotionally, but in...
Read article