Having migraines does not lead to brain damage with age

October 17, 2024

If you’re one of the millions of people who suffer from migraines, you might be worried about the long-term effects on your brain. Recent studies have suggested that people with migraines might be at higher risk for structural brain changes, such as damage to small vessels in the brain and shrinkage of the brain or brain atrophy.

A recent study published in Cephalalgia by Dutch researchers examined the connection between migraines and brain health in over 4,900 middle-aged and elderly people. The researchers used magnetic resonance imaging (MRI) to study the brains of the participants and assess any structural changes.

The study found that people with migraines were not any more likely to have structural brain changes than those without migraines. There were no significant differences between the two groups in terms of:

  • Total brain volume
  • Grey matter volume
  • White matter volume
  • White matter hyperintensity volume (a marker for small vessel disease)
  • Presence of lacunes (tiny holes in the brain)
  • Presence of cerebral microbleeds (small bleeds in the brain)

This study suggests that having migraines may not increase your risk of developing structural brain changes as you age. This is reassuring news for people who suffer from migraines and are concerned about the long-term effects on their brain health.

Written by
Alexander Mauskop, MD
Continue reading
July 18, 2026
Alternative Therapies
Why Everyone Should Have Their Vitamin D Level Checked, And Why 'Normal' Isn't Good Enough
Vitamin D deficiency is common, often missed, and easy to correct. In this post I explain why “normal” lab values can be misleading, how vitamin D affects headaches, heart and brain health, and what levels and doses I recommend for my patients.
Read article
July 13, 2026
Brain disorders
fMRI-guidedTMS targeting improves outcomes
This post reviews new data showing that fMRI‑guided, connectivity‑based TMS targeting improves response rates in treatment‑resistant depression and likely other conditions. By mapping each patient’s brain circuits, clinicians can move beyond a one‑size‑fits‑all DLPFC target to condition‑specific and patient‑specific sites, a particularly important advance for migraine and network‑based pain disorders.
Read article
July 3, 2026
Alternative Therapies
Essential Oils Can Change Your Brain
The science of essential oils and the brain is still young, but the findings so far are more compelling than many people realize. Brain imaging studies show that common scents like rose, lavender, peppermint, and lemon produce measurable changes in brain structure, brain activity, and pain processing. These studies are small and preliminary, and essential oils are not a substitute for medical treatment. But the evidence suggests that what we smell can influence the brain in real, physical ways
Read article
Insights from Dr. Alexander Mauskop on headaches and migraines
Subscribe to the Blog.
Subscribe
Subscribe