Intranasal use of capsaicin (on the side of the headache) has been reported to relieve cluster headaches. Capsaicin is an extract of hot peppers and can cause burning pain and irritation of the nasal mucosa. It must be used twice a day for several days before improvement is noticed. Intranasal use of capsaicin (on the side of the headache) has been reported to relieve cluster headaches. Capsaicin is an extract of hot peppers and can cause burning pain and irritation of the nasal mucosa. It must be used twice a day for several days before improvement is noticed.
A study published in Neurology, the journal of the American Academy of Neurology, indicates that oral zolmitriptan (Zomig) is effective in the treatment of cluster headaches. The study used a 10 mg dose, which exceeds the FDA-approved maximum dose of 5 mg for migraines. However, oxygen inhalation and injectable sumatriptan (Imitrex), when effective, usually provide faster relief.
Prophylactic treatment
Several reports suggest that in addition to such standard therapies as Depakote, verapamil, and lithium a nightly 10 mg dose of over-the-counter melatonin can prevent cluster headaches in some patients. Since a short course of melatonin is very safe, it is worth a try after consultation with your physician.
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