Brain is damaged by repeated head trauma, even without a concussion

May 1, 2018

A group of American and Israeli researchers published a study in the journal Brain, suggesting that hits to the head, even those that do not cause an overt concussion, contribute to the chronic traumatic encephalopathy (CTE). CTE has been found in many football players, combat veterans, and other athletes who suffer from repeated head injuries.

The current study examined brains of four teenage athletes who had sustained repetitive hits to the head in the days and weeks before their death. They did not have typical symptoms of concussion – headaches, dizziness, confusion, memory difficulties, or vision problems. One of them had an early-stage CE and two had accumulation of tau protein that is implicated in CTE and Alzheimer’s disease.

These researchers proceeded to create a mouse model of repetitive and subconcussive head trauma, which also showed that relatively mild repetitive head injuries lead to degenerative changes in the brain.

These findings are not very surprising – repeatedly hitting your head cannot be good for your brain, regardless of the severity of each injury. However, many questions remain unanswered – what is the role of certain genetic traits that are known to predispose to CTE, could magnesium, which is depleted by trauma, or other supplements help reduce the damage, and what other interventions could possibly protect the brain.

Written by
Alexander Mauskop, MD
Continue reading
September 7, 2025
How Artificial Sweeteners May Be Affecting Your Brain
A large Brazilian study published in Neurology followed nearly 13,000 adults for eight years and found something troubling: people who consumed the most artificial sweeteners showed faster cognitive...
Read article
August 30, 2025
Lithium Levels are low in Alzheimer’s. Is there a role in Migraine and Chronic Pain?
Recently published research on lithium deficiency in Alzheimer’s disease has caught the attention of the media. As a neurologist specializing in pain and headache medicine with an interest in no...
Read article
August 16, 2025
The Healing Power of Holding Hands: Insights from Neuroscience on Pain Relief
There’s something powerful about human touch when you’re hurting. As a neurologist, I see every day how a gentle hand squeeze from someone you trust can shift your pain—not just emotionally, but in...
Read article