Sinus infection usually does not require antibiotics

February 23, 2012

Migraines are often mistaken for sinus infections, and are treated with antibiotics. The reson for this confusion is that migraines can cause pain in the area of sinuses and some people will even have a clear discharge from their nose during a migraine attack. Sinus infection is really easy to diagnose – it usually causes a yellow or green discharge from the nose. But even if you do have a true sinus infections antibiotics are usually unnecessary because the infection is caused by a virus and viral infections do not respond to antibiotics. This well-know fact is confirmed in a new study which was just published in the Journal of the American Medical Association. The study involved 166 adults with a sinus infection who were given either a placebo or an antibiotic for 10 days. There was no difference between the two groups in the satisfaction with the treatment, the amount of time missed from work, and every other parameter measured. The authors (doctors at Washington University in St. Louis) do recommend starting antibiotics if the condition does not after 5 – 7 days.

Written by
Alexander Mauskop, MD
Continue reading
May 10, 2026
Research
Elismetrep: A Promising New Experimental Migraine Treatment
Elismetrep is a promising experimental migraine medication that targets the TRPM8 pathway rather than serotonin or CGRP. Early clinical trials suggest it may offer a new option for patients who do not respond well to current treatments.
Read article
May 6, 2026
Alternative Therapies
New Research on Brain Excitability and TMS Treatment for Migraine
New research shows how the brain dynamically regulates excitability in real time—and why this matters for transcranial magnetic stimulation (TMS) as a treatment for migraine.
Read article
April 20, 2026
Can the Air You Breathe and the Weather Outside Trigger Your Migraines?
A major new study of over 7,000 migraine patients tracked two decades of air pollution, temperature, and humidity data, and found that the environment isn't just a background player. It's an active trigger.
Read article
Insights from Dr. Alexander Mauskop on headaches and migraines
Subscribe to the Blog.
Subscribe
Subscribe